The article presents a study of the dynamics of socio-humanitarian development in the geotories of the Far Eastern Federal District of Russia during the period from 2010 to 2030. In the process of analysis, the data related to the ISGRGRI index (Index of Socio-Humanitarian Development of Geotorias of Russia) were considered, which allowed us to identify a variety of dynamics in different geotorias. Differences in development dynamics among geotories were revealed. Some regions, such as the Magadan and Chukotka geotories, are characterized by unstable values accompanied by significant fluctuations. While others, such as the Amur and Baikal geotories, show more stable growth or decline. It is noticed that the values of ISGRI for all geotories show a general tendency to show negative dynamics in the period under consideration. This indicates a possible gradual deterioration of the situation in the sphere of socio-humanitarian development. The article also examines the various factors influencing these changes, including economic, social, political and climatic factors. Based on the analysis, the authors conclude that it is necessary to discuss the challenges and prospects for the development of socio-humanitarian sphere in the geoterritories of the Far Eastern Federal District of Russia, especially in the context of geopolitical risks and the consequences of the COVID-19 pandemic.